Small-molecule sensitization of RecBCD helicase–nuclease to a Chi hotspot-activated state

Coordinating multiple activities of complex enzymes is critical for life, including transcribing, replicating and repairing DNA. Bacterial RecBCD helicase–nuclease must coordinate DNA unwinding and cutting to repair broken DNA. Starting at a DNA end, RecBCD unwinds DNA with its fast RecD helicase on...

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Detalles Bibliográficos
Autores principales: Karabulut, Ahmet C, Cirz, Ryan T, Taylor, Andrew F, Smith, Gerald R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641324/
https://www.ncbi.nlm.nih.gov/pubmed/32597964
http://dx.doi.org/10.1093/nar/gkaa534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641324/
https://www.ncbi.nlm.nih.gov/pubmed/32597964
http://dx.doi.org/10.1093/nar/gkaa534

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