Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication

The eukaryotic replisome must faithfully replicate DNA and cope with replication fork blocks and stalling, while simultaneously promoting sister chromatid cohesion. Ctf18-RFC is an alternative PCNA loader that links all these processes together by an unknown mechanism. Here, we use integrative struc...

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Detalles Bibliográficos
Autores principales: Stokes, Katy, Winczura, Alicja, Song, Boyuan, De Piccoli, Giacomo, Grabarczyk, Daniel B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641331/
https://www.ncbi.nlm.nih.gov/pubmed/32585006
http://dx.doi.org/10.1093/nar/gkaa541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641331/
https://www.ncbi.nlm.nih.gov/pubmed/32585006
http://dx.doi.org/10.1093/nar/gkaa541

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