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Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials

BACKGROUND: The tumor microenvironment (TME) is increasingly appreciated as an important determinant of cancer outcome, including in multiple myeloma (MM). However, most myeloma microenvironment studies have been based on bone marrow (BM) aspirates, which often do not fully reflect the cellular cont...

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Detalles Bibliográficos
Autores principales: Danziger, Samuel A., McConnell, Mark, Gockley, Jake, Young, Mary H., Rosenthal, Adam, Schmitz, Frank, Reiss, David J., Farmer, Phil, Alapat, Daisy V., Singh, Amrit, Ashby, Cody, Bauer, Michael, Ren, Yan, Smith, Kelsie, Couto, Suzana S., van Rhee, Frits, Davies, Faith, Zangari, Maurizio, Petty, Nathan, Orlowski, Robert Z., Dhodapkar, Madhav V., Copeland, Wilbert B., Fox, Brian, Hoering, Antje, Fitch, Alison, Newhall, Katie, Barlogie, Bart, Trotter, Matthew W. B., Hershberg, Robert M., Walker, Brian A., Dervan, Andrew P., Ratushny, Alexander V., Morgan, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641353/
https://www.ncbi.nlm.nih.gov/pubmed/33147277
http://dx.doi.org/10.1371/journal.pmed.1003323