Cargando…

Loss of hepatocyte cell division leads to liver inflammation and fibrosis

The liver possesses a remarkable regenerative capacity based partly on the ability of hepatocytes to re-enter the cell cycle and divide to replace damaged cells. This capability is substantially reduced upon chronic damage, but it is not clear if this is a cause or consequence of liver disease. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Dewhurst, Matthew R., Ow, Jin Rong, Zafer, Gözde, van Hul, Noémi K. M., Wollmann, Heike, Bisteau, Xavier, Brough, David, Choi, Hyungwon, Kaldis, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641358/
https://www.ncbi.nlm.nih.gov/pubmed/33147210
http://dx.doi.org/10.1371/journal.pgen.1009084