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Diffusion vs. direct transport in the precision of morphogen readout

Morphogen profiles allow cells to determine their position within a developing organism, but not all morphogen profiles form by the same mechanism. Here, we derive fundamental limits to the precision of morphogen concentration sensing for two canonical mechanisms: the diffusion of morphogen through...

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Detalles Bibliográficos
Autores principales: Fancher, Sean, Mugler, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641583/
https://www.ncbi.nlm.nih.gov/pubmed/33051001
http://dx.doi.org/10.7554/eLife.58981