ONC206, an Imipridone Derivative, Induces Cell Death Through Activation of the Integrated Stress Response in Serous Endometrial Cancer In Vitro

ONC206 (Oncoceutics) is an imipiridone with nanomolar potency and analogue of ONC201, a selective dopamine receptor D2 (DRD2) antagonist currently being investigated in phase II clinical trials for serous endometrial cancer (SEC). This study investigated the anti-proliferative efficacy of ONC206 in...

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Detalles Bibliográficos
Autores principales: Zhang, Yingao, Huang, Yu, Yin, Yajie, Fan, Yali, Sun, Wenchuan, Zhao, Xiaoling, Tucker, Katherine, Staley, Allison, Paraghamian, Sarah, Hawkins, Gabrielle, Prabhu, Varun, Allen, Joshua E., Zhou, Chunxiao, Bae-Jump, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641618/
https://www.ncbi.nlm.nih.gov/pubmed/33194693
http://dx.doi.org/10.3389/fonc.2020.577141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641618/
https://www.ncbi.nlm.nih.gov/pubmed/33194693
http://dx.doi.org/10.3389/fonc.2020.577141

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