Mechanism of Paeoniflorin in the Treatment of Bile Duct Ligation-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology

Paeoniflorin (PF) is the main active component of Paeonia lactiflora Pall., which is used in the treatment of severe cholestatic hepatitis. However, its biological mechanism in regulating bile acid metabolism and cholestatic liver injury has not been fully revealed. Our study aimed to reveal the mec...

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Detalles Bibliográficos
Autores principales: Wei, Shizhang, Ma, Xiao, Niu, Ming, Wang, Ruilin, Yang, Tao, Wang, Dan, Wen, Jianxia, Li, Haotian, Zhao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641625/
https://www.ncbi.nlm.nih.gov/pubmed/33192530
http://dx.doi.org/10.3389/fphar.2020.586806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641625/
https://www.ncbi.nlm.nih.gov/pubmed/33192530
http://dx.doi.org/10.3389/fphar.2020.586806

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