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ERBB2-CAR-Engineered Cytokine-Induced Killer Cells Exhibit Both CAR-Mediated and Innate Immunity Against High-Risk Rhabdomyosarcoma

High-risk rhabdomyosarcoma (RMS) occurring in childhood to young adulthood is associated with a poor prognosis; especially children above the age of 10 with advanced stage alveolar RMS still succumb to the disease within a median of 2 years. The advent of chimeric antigen receptor (CAR)-engineered T...

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Detalles Bibliográficos
Autores principales: Merker, Michael, Wagner, Juliane, Kreyenberg, Hermann, Heim, Catrin, Moser, Laura M., Wels, Winfried S., Bonig, Halvard, Ivics, Zoltán, Ullrich, Evelyn, Klingebiel, Thomas, Bader, Peter, Rettinger, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641627/
https://www.ncbi.nlm.nih.gov/pubmed/33193388
http://dx.doi.org/10.3389/fimmu.2020.581468