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A Shaking-Culture Method for Generating Bone Marrow Derived Mesenchymal Stromal/Stem Cell-Spheroids With Enhanced Multipotency in vitro

Mesenchymal stromal/stem cells (MSCs), which generally expand into adherent monolayers, readily lose their proliferative and multilineage potential following repeated passages. Floating culture systems can be used to generate MSC spheroids, which are expected to overcome limitations associated with...

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Detalles Bibliográficos
Autores principales: Niibe, Kunimichi, Ohori-Morita, Yumi, Zhang, Maolin, Mabuchi, Yo, Matsuzaki, Yumi, Egusa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641632/
https://www.ncbi.nlm.nih.gov/pubmed/33195156
http://dx.doi.org/10.3389/fbioe.2020.590332