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Acacetin Suppresses IL-1β-Induced Expression of Matrix Metalloproteinases in Chondrocytes and Protects against Osteoarthritis in a Mouse Model by Inhibiting NF-κB Signaling Pathways

Osteoarthritis (OA) is a very common chronic joint dysfunction, and there is currently a poor understanding of its etiology and pathogenesis. Therefore, there are no active disease-modifying drugs currently available for clinical treatment. Several natural compounds have been shown to play a role in...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Wang, Chen, Huang, Kangmao, Chen, Shuai, Ma, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641688/
https://www.ncbi.nlm.nih.gov/pubmed/33195691
http://dx.doi.org/10.1155/2020/2328401