The HMGB chromatin protein Nhp6A can bypass obstacles when traveling on DNA

DNA binding proteins rapidly locate their specific DNA targets through a combination of 3D and 1D diffusion mechanisms, with the 1D search involving bidirectional sliding along DNA. However, even in nucleosome-free regions, chromosomes are highly decorated with associated proteins that may block sli...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamagata, Kiyoto, Ouchi, Kana, Tan, Cheng, Mano, Eriko, Mandali, Sridhar, Wu, Yining, Takada, Shoji, Takahashi, Satoshi, Johnson, Reid C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641734/
https://www.ncbi.nlm.nih.gov/pubmed/32997109
http://dx.doi.org/10.1093/nar/gkaa799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641734/
https://www.ncbi.nlm.nih.gov/pubmed/32997109
http://dx.doi.org/10.1093/nar/gkaa799

Ejemplares similares