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Crystal structure of the Cenp-HIK(Head)-TW sub-module of the inner kinetochore CCAN complex

Kinetochores are large multi-subunit complexes that attach centromeric chromatin to microtubules of the mitotic spindle, enabling sister chromatid segregation in mitosis. The inner kinetochore constitutive centromere associated network (CCAN) complex assembles onto the centromere-specific Cenp-A nuc...

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Detalles Bibliográficos
Autores principales: Zhang, Ziguo, Bellini, Dom, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641736/
https://www.ncbi.nlm.nih.gov/pubmed/32976599
http://dx.doi.org/10.1093/nar/gkaa772