ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B–H4K8ac–BRD4 axis

Centromeres are genomic regions essential for faithful chromosome segregation. Transcription of noncoding RNA (ncRNA) at centromeres is important for their formation and functions. Here, we report the molecular mechanism by which the transcriptional regulator ZFAT controls the centromeric ncRNA tran...

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Detalles Bibliográficos
Autores principales: Ishikura, Shuhei, Nakabayashi, Kazuhiko, Nagai, Masayoshi, Tsunoda, Toshiyuki, Shirasawa, Senji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641738/
https://www.ncbi.nlm.nih.gov/pubmed/32997115
http://dx.doi.org/10.1093/nar/gkaa815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641738/
https://www.ncbi.nlm.nih.gov/pubmed/32997115
http://dx.doi.org/10.1093/nar/gkaa815

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