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ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B–H4K8ac–BRD4 axis
Centromeres are genomic regions essential for faithful chromosome segregation. Transcription of noncoding RNA (ncRNA) at centromeres is important for their formation and functions. Here, we report the molecular mechanism by which the transcriptional regulator ZFAT controls the centromeric ncRNA tran...
Autores principales: | Ishikura, Shuhei, Nakabayashi, Kazuhiko, Nagai, Masayoshi, Tsunoda, Toshiyuki, Shirasawa, Senji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641738/ https://www.ncbi.nlm.nih.gov/pubmed/32997115 http://dx.doi.org/10.1093/nar/gkaa815 |
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