HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression

Although endogenous retroviruses (ERVs) are known to harbor cis-regulatory elements, their role in modulating cellular immune responses remains poorly understood. Using an RNA-seq approach, we show that several members of the ERV9 lineage, particularly LTR12C elements, are activated upon HIV-1 infec...

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Detalles Bibliográficos
Autores principales: Srinivasachar Badarinarayan, Smitha, Shcherbakova, Irina, Langer, Simon, Koepke, Lennart, Preising, Andrea, Hotter, Dominik, Kirchhoff, Frank, Sparrer, Konstantin M J, Schotta, Gunnar, Sauter, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641743/
https://www.ncbi.nlm.nih.gov/pubmed/33021676
http://dx.doi.org/10.1093/nar/gkaa832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641743/
https://www.ncbi.nlm.nih.gov/pubmed/33021676
http://dx.doi.org/10.1093/nar/gkaa832

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