METTL3 counteracts premature aging via m(6)A-dependent stabilization of MIS12 mRNA

N(6)-Methyladenosine (m(6)A) messenger RNA methylation is a well-known epitranscriptional regulatory mechanism affecting central biological processes, but its function in human cellular senescence remains uninvestigated. Here, we found that levels of both m(6)A RNA methylation and the methyltransfer...

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Detalles Bibliográficos
Autores principales: Wu, Zeming, Shi, Yue, Lu, Mingming, Song, Moshi, Yu, Zihui, Wang, Jilu, Wang, Si, Ren, Jie, Yang, Yun-Gui, Liu, Guang-Hui, Zhang, Weiqi, Ci, Weimin, Qu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641765/
https://www.ncbi.nlm.nih.gov/pubmed/33035345
http://dx.doi.org/10.1093/nar/gkaa816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641765/
https://www.ncbi.nlm.nih.gov/pubmed/33035345
http://dx.doi.org/10.1093/nar/gkaa816

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