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Chromosomal aberration arises during somatic reprogramming to pluripotent stem cells

BACKGROUND: Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) has opened new therapeutic possibilities. However, karyotypic abnormalities detected in iPSCs compromised their utility, especially chromosomal aberrations found at early passages raised serious safety concerns. The me...

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Detalles Bibliográficos
Autores principales:	Liu, Xinyu, Li, Conghui, Zheng, Kang, Zhao, Xiaofeng, Xu, Xiaofeng, Yang, Aifen, Yi, Min, Tao, Huaping, Xie, Binghua, Qiu, Mengsheng, Yang, Junlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641821/ https://www.ncbi.nlm.nih.gov/pubmed/33292330 http://dx.doi.org/10.1186/s13008-020-00068-z

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