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A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer

BACKGROUND: The role of nuclear receptors in both the aetiology and treatment of breast cancer is exemplified by the use of the oestrogen receptor (ER) as a prognostic marker and treatment target. Treatments targeting the oestrogen signalling pathway are initially highly effective for most patients....

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Detalles Bibliográficos
Autores principales: Doan, Tram B., Cheung, Vanessa, Clyne, Colin D., Hilton, Heidi N., Eriksson, Natalie, Young, Morag J., Funder, John W., Muscat, George E. O., Fuller, Peter J., Clarke, Christine L., Graham, J. Dinny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641839/
https://www.ncbi.nlm.nih.gov/pubmed/33148314
http://dx.doi.org/10.1186/s13058-020-01355-x