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High proportion of anergic B cells in the bone marrow defined phenotypically by CD21(−/low)/CD38- expression predicts poor survival in diffuse large B cell lymphoma

BACKGROUND: Diffuse large B cell lymphoma (DLBCL) is the commonest lymphoma that is highly aggressive where one-third of the patients relapse despite effective treatment. Interaction between the lymphoma cells and the non-clonal immune cells within the bone marrow microenvironment is thought to play...

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Detalles Bibliográficos
Autores principales: Rijal, Sewa, Kok, Johanna, Coombes, Caitlin, Smyth, Lillian, Hourigan, Jayde, Jain, Sanjiv, Talaulikar, Dipti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641859/
https://www.ncbi.nlm.nih.gov/pubmed/33143694
http://dx.doi.org/10.1186/s12885-020-07525-6