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Neutrophil Elastase Inhibitor Sivelestat Attenuates Myocardial Injury after Cardioplegic Arrest in Rat Hearts

Purpose: Sivelestat, a neutrophil elastase inhibitor, attenuates global ischemia-induced myocardial damage and coronary endothelial dysfunction. Here, we investigated whether sivelestat exerts the cardioprotective effects against cardioplegic arrest in rat hearts. Methods: Isolated Langendorff-perfu...

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Detalles Bibliográficos
Autores principales: Fujii, Masahiro, Bessho, Ryuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641891/
https://www.ncbi.nlm.nih.gov/pubmed/31813921
http://dx.doi.org/10.5761/atcs.oa.19-00240