Use of human splenocytes in an innovative humanised mouse model for prediction of immunotherapy‐induced cytokine release syndrome

OBJECTIVES: Humanised mice have emerged as valuable models for pre‐clinical testing of the safety and efficacy of immunotherapies. Given the variety of models available, selection of the most appropriate humanised mouse model is critical in study design. Here, we aimed to develop a model for predict...

Descripción completa

Detalles Bibliográficos
Autores principales: Matas‐Céspedes, Alba, Brown, Lee, Mahbubani, Krishnaa T, Bareham, Bethany, Higgins, Jackie, Curran, Michelle, de Haan, Lolke, Lapointe, Jean‐Martin, Stebbings, Richard, Saeb‐Parsy, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641894/
https://www.ncbi.nlm.nih.gov/pubmed/33173582
http://dx.doi.org/10.1002/cti2.1202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641894/
https://www.ncbi.nlm.nih.gov/pubmed/33173582
http://dx.doi.org/10.1002/cti2.1202

Ejemplares similares