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Scutellarin Ameliorates Renal Injury via Increasing CCN1 Expression and Suppressing NLRP3 Inflammasome Activation in Hyperuricemic Mice

Considerable evidences have indicated that elevated uric acid (UA) was involved in renal tubular injury leading to hyperuricemic nephropathy (HN). Scutellarin is a biologically active flavonoid derived from the Chinese traditional herb Erigeron breviscapus Hand-Mazz, which has been widely used in th...

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Detalles Bibliográficos
Autores principales: Li, Guozheng, Guan, Chen, Xu, Lingyu, Wang, Lin, Yang, Chengyu, Zhao, Long, Zhou, Bin, Luo, Congjuan, Luan, Hong, Jiang, Wei, Li, Chenyu, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641948/
https://www.ncbi.nlm.nih.gov/pubmed/33192525
http://dx.doi.org/10.3389/fphar.2020.584942