Cargando…

Scutellarin Ameliorates Renal Injury via Increasing CCN1 Expression and Suppressing NLRP3 Inflammasome Activation in Hyperuricemic Mice

Considerable evidences have indicated that elevated uric acid (UA) was involved in renal tubular injury leading to hyperuricemic nephropathy (HN). Scutellarin is a biologically active flavonoid derived from the Chinese traditional herb Erigeron breviscapus Hand-Mazz, which has been widely used in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Guozheng, Guan, Chen, Xu, Lingyu, Wang, Lin, Yang, Chengyu, Zhao, Long, Zhou, Bin, Luo, Congjuan, Luan, Hong, Jiang, Wei, Li, Chenyu, Xu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641948/ https://www.ncbi.nlm.nih.gov/pubmed/33192525 http://dx.doi.org/10.3389/fphar.2020.584942

Ejemplares similares

Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis
por: Liu, Yi, et al.
Publicado: (2018)

Effects of Shizhifang on NLRP3 Inflammasome Activation and Renal Tubular Injury in Hyperuricemic Rats
por: Wu, Yansheng, et al.
Publicado: (2017)

Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice
por: Xu, Lieqiang, et al.
Publicado: (2021)

Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome
por: Hou, Qing, et al.
Publicado: (2022)

Crucial role of serum response factor in renal tubular epithelial cell epithelial-mesenchymal transition in hyperuricemic nephropathy
por: Zhao, Long, et al.
Publicado: (2019)

Sinapine Thiocyanate Ameliorates Vascular Endothelial Dysfunction in Hypertension by Inhibiting Activation of the NLRP3 Inflammasome
por: Liu, Yang, et al.
Publicado: (2021)

Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway
por: Zhang, Ningxin, et al.
Publicado: (2022)

Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation
por: Ye, Tianyuan, et al.
Publicado: (2018)

Mangiferin Ameliorates Hyperuricemic Nephropathy Which Is Associated With Downregulation of AQP2 and Increased Urinary Uric Acid Excretion
por: Li, Xuechen, et al.
Publicado: (2020)

Blockade of Autophagy Prevents the Progression of Hyperuricemic Nephropathy Through Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis
por: Hu, Yan, et al.
Publicado: (2022)

Berberine Protects Against NLRP3 Inflammasome via Ameliorating Autophagic Impairment in MPTP-Induced Parkinson’s Disease Model
por: Huang, Shuxuan, et al.
Publicado: (2021)

Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis
por: Liao, Chuyao, et al.
Publicado: (2022)

NLRP3 inflammasome and its inhibitors: a review
por: Shao, Bo-Zong, et al.
Publicado: (2015)

Tilianin Reduces Apoptosis via the ERK/EGR1/BCL2L1 Pathway in Ischemia/Reperfusion-Induced Acute Kidney Injury Mice
por: Liu, Zengying, et al.
Publicado: (2022)

Yanghe Decoction Suppresses the Experimental Autoimmune Thyroiditis in Rats by Improving NLRP3 Inflammasome and Immune Dysregulation
por: Ma, Bing’e, et al.
Publicado: (2021)

Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation
por: Li, Xiaoling, et al.
Publicado: (2022)

Neurodegenerative Disease and the NLRP3 Inflammasome
por: Holbrook, Jonathan A., et al.
Publicado: (2021)

4-Methylesculetin ameliorates LPS-induced depression-like behavior through the inhibition of NLRP3 inflammasome
por: Choudhary, Khushboo, et al.
Publicado: (2023)

Role of NLRP3 inflammasome and oxidative stress in hepatic insulin resistance and the ameliorative effect of phytochemical intervention
por: de Deus, Isabela Jesus, et al.
Publicado: (2023)

(−)-Epicatechin Ameliorates Monosodium Urate-Induced Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and the NF-κB Signaling Pathway
por: Wu, Chenxi, et al.
Publicado: (2022)

Zerumbone Suppresses the LPS-Induced Inflammatory Response and Represses Activation of the NLRP3 Inflammasome in Macrophages
por: Su, Chia-Cheng, et al.
Publicado: (2021)

Gallic acid ameliorates dextran sulfate sodium-induced ulcerative colitis in mice via inhibiting NLRP3 inflammasome
por: Yu, Tian-Yuan, et al.
Publicado: (2023)

Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination
por: Zhao, Xibao, et al.
Publicado: (2017)

The role of NLRP3 inflammasome in hepatocellular carcinoma
por: Zhao, Huijie, et al.
Publicado: (2023)

Norcantharidin ameliorates estrogen deficient-mediated bone loss by attenuating the activation of extracellular signal-regulated kinase/ROS/NLRP3 inflammasome signaling
por: Yang, Guang, et al.
Publicado: (2022)

Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke
por: Du, Xiaoxue, et al.
Publicado: (2023)

Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells
por: Liu, Ming, et al.
Publicado: (2020)

Protective Property of Scutellarin Against Liver Injury Induced by Carbon Tetrachloride in Mice
por: Miao, Zhimin, et al.
Publicado: (2021)

Atractylenolide I Inhibits NLRP3 Inflammasome Activation in Colitis-Associated Colorectal Cancer via Suppressing Drp1-Mediated Mitochondrial Fission
por: Qin, Yao, et al.
Publicado: (2021)

The NLRP3 Inflammasome in Non-Alcoholic Fatty Liver Disease and Steatohepatitis: Therapeutic Targets and Treatment
por: Yu, Lili, et al.
Publicado: (2022)

Inonotus obliquus Polysaccharide Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Cancer in Mice via Activation of the NLRP3 Inflammasome
por: Li, Jiawei, et al.
Publicado: (2021)

Activation of Platelet NLRP3 Inflammasome in Crohn’s Disease
por: Zhang, Ge, et al.
Publicado: (2021)

C646 Protects Against DSS-Induced Colitis Model by Targeting NLRP3 Inflammasome
por: Xu, Xueming, et al.
Publicado: (2021)

Pharmacologic Targeting of BET Proteins Attenuates Hyperuricemic Nephropathy in Rats
por: Xiong, Chongxiang, et al.
Publicado: (2021)

Canagliflozin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Inhibiting NF-κB Signaling and Upregulating Bif-1
por: Niu, Yaoyun, et al.
Publicado: (2022)

Aspirin-triggered Resolvin D1 ameliorates activation of the NLRP3 inflammasome via induction of autophagy in a rat model of neuropathic pain
por: Wang, Yi-Hao, et al.
Publicado: (2023)

Harmine Ameliorates Cognitive Impairment by Inhibiting NLRP3 Inflammasome Activation and Enhancing the BDNF/TrkB Signaling Pathway in STZ-Induced Diabetic Rats
por: Liu, Peifang, et al.
Publicado: (2020)

Scutellarin Reduce the Homocysteine Level and Alleviate Liver Injury in Type 2 Diabetes Model
por: Wang, Yiyu, et al.
Publicado: (2020)

Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling
por: Lu, Miaomiao, et al.
Publicado: (2017)

Scutellarin Attenuates the IL-1β-Induced Inflammation in Mouse Chondrocytes and Prevents Osteoarthritic Progression
por: Luo, Zucheng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vpkljqmqt6j3d7pnsli0fs1cub