Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

AIMS/HYPOTHESIS: In islets from individuals with type 2 diabetes and in islets exposed to chronic elevated glucose, mitochondrial energy metabolism is impaired. Here, we studied early metabolic changes and mitochondrial adaptations in human beta cells during chronic glucose stress. METHODS: Respirat...

Descripción completa

Detalles Bibliográficos
Autores principales: Chareyron, Isabelle, Christen, Stefan, Moco, Sofia, Valsesia, Armand, Lassueur, Steve, Dayon, Loïc, Wollheim, Claes B., Santo Domingo, Jaime, Wiederkehr, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641954/
https://www.ncbi.nlm.nih.gov/pubmed/32960311
http://dx.doi.org/10.1007/s00125-020-05275-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641954/
https://www.ncbi.nlm.nih.gov/pubmed/32960311
http://dx.doi.org/10.1007/s00125-020-05275-5

Ejemplares similares