Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung

Aberrant epithelial reprogramming can induce metaplastic differentiation at sites of tissue injury, culminating in transformed barriers composed of scar and metaplastic epithelium. While the plasticity of epithelial stem cells is well-characterized, the identity and role of the niche has not been de...

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Detalles Bibliográficos
Autores principales: Cassandras, Monica, Wang, Chaoqun, Kathiriya, Jaymin, Tsukui, Tatsuya, Matatia, Peri, Matthay, Michael, Wolters, Paul, Molofsky, Ari, Sheppard, Dean, Chapman, Hal, Peng, Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642162/
https://www.ncbi.nlm.nih.gov/pubmed/33046884
http://dx.doi.org/10.1038/s41556-020-00591-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642162/
https://www.ncbi.nlm.nih.gov/pubmed/33046884
http://dx.doi.org/10.1038/s41556-020-00591-9

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