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Predicting Cross-Reactivity and Antigen Specificity of T Cell Receptors

Adaptive immune recognition is mediated by specific interactions between heterodimeric T cell receptors (TCRs) and their cognate peptide-MHC (pMHC) ligands, and the methods to accurately predict TCR:pMHC interaction would have profound clinical, therapeutic and pharmaceutical applications. Herein, w...

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Detalles Bibliográficos
Autores principales: Lee, Chloe H., Salio, Mariolina, Napolitani, Giorgio, Ogg, Graham, Simmons, Alison, Koohy, Hashem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642207/
https://www.ncbi.nlm.nih.gov/pubmed/33193332
http://dx.doi.org/10.3389/fimmu.2020.565096