Cargando…

Predicting Cross-Reactivity and Antigen Specificity of T Cell Receptors

Adaptive immune recognition is mediated by specific interactions between heterodimeric T cell receptors (TCRs) and their cognate peptide-MHC (pMHC) ligands, and the methods to accurately predict TCR:pMHC interaction would have profound clinical, therapeutic and pharmaceutical applications. Herein, w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Chloe H., Salio, Mariolina, Napolitani, Giorgio, Ogg, Graham, Simmons, Alison, Koohy, Hashem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642207/ https://www.ncbi.nlm.nih.gov/pubmed/33193332 http://dx.doi.org/10.3389/fimmu.2020.565096

Ejemplares similares

Potential CD8+ T Cell Cross-Reactivity Against SARS-CoV-2 Conferred by Other Coronavirus Strains
por: Lee, Chloe H., et al.
Publicado: (2020)

Regulation of Lipid Specific and Vitamin Specific Non-MHC Restricted T Cells by Antigen Presenting Cells and Their Therapeutic Potentials
por: Salio, Mariolina, et al.
Publicado: (2015)

Elevated and cross‐responsive CD1a‐reactive T cells in bee and wasp venom allergic individuals
por: Subramaniam, Sumithra, et al.
Publicado: (2015)

HLA‐dependent variation in SARS‐CoV‐2 CD8 (+) T cell cross‐reactivity with human coronaviruses
por: Buckley, Paul R., et al.
Publicado: (2022)

Cross‐reactivity of hepatitis C virus specific vaccine‐induced T cells at immunodominant epitopes
por: Kelly, Christabel, et al.
Publicado: (2014)

Can we predict T cell specificity with digital biology and machine learning?
por: Hudson, Dan, et al.
Publicado: (2023)

Harnessing the Power of Invariant Natural Killer T Cells in Cancer Immunotherapy
por: Bedard, Melissa, et al.
Publicado: (2017)

The Immune Modulating Properties of Mucosal-Associated Invariant T Cells
por: Ioannidis, Melina, et al.
Publicado: (2020)

MR1-Restricted Mucosal-Associated Invariant T Cells and Their Activation during Infectious Diseases
por: Howson, Lauren J., et al.
Publicado: (2015)

Degradation of T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation
por: Valitutti, Salvatore, et al.
Publicado: (1997)

A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responses
por: Buckley, Paul R, et al.
Publicado: (2023)

Quantitative Contribution of CD4 and CD8 to T Cell Antigen Receptor Serial Triggering
por: Viola, Antonella, et al.
Publicado: (1997)

In silico identification of vaccine targets for 2019-nCoV
por: Lee, Chloe H., et al.
Publicado: (2020)

A robust deep learning workflow to predict CD8 + T-cell epitopes
por: Lee, Chloe H., et al.
Publicado: (2023)

Antigenic Cross-Reactivity Between SARS-CoV-2 S1-RBD and Its Receptor ACE2
por: Lai, Yen-Chung, et al.
Publicado: (2022)

Linking Inflammation to Natural Killer T Cell Activation
por: Salio, Mariolina, et al.
Publicado: (2009)

Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion
por: Aulicino, Anna, et al.
Publicado: (2022)

Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination
por: Matheson, Louise S., et al.
Publicado: (2017)

A lesson from the ice bucket challenge: using social networks to publicize science
por: Koohy, Hashem, et al.
Publicado: (2014)

HLA variants have different preferences to present proteins with specific molecular functions which are complemented in frequent haplotypes
por: Karnaukhov, Vadim, et al.
Publicado: (2022)

Antigen-Specific T-Cell Activation Independently of the MHC: Chimeric Antigen Receptor-Redirected T Cells
por: Chmielewski, Markus, et al.
Publicado: (2013)

Selective Inhibition of Ii-dependent Antigen Presentation by Helicobacter pylori Toxin VacA
por: Molinari, Maurizio, et al.
Publicado: (1998)

CpG-matured Murine Plasmacytoid Dendritic Cells Are Capable of In Vivo Priming of Functional CD8 T Cell Responses to Endogenous but Not Exogenous Antigens
por: Salio, Mariolina, et al.
Publicado: (2004)

Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens
por: Buckley, Paul R, et al.
Publicado: (2022)

Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells
por: Salio, Mariolina, et al.
Publicado: (2017)

Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
por: Crump, Nicholas T., et al.
Publicado: (2021)

Immune Response Regulation by Antigen Receptors’ Clone-Specific Nonself Parts
por: Lemke, Hilmar
Publicado: (2018)

Protection of Grouper Against Cryptocaryon irritans by Immunization With Tetrahymena thermophila and Protective Cross-Reactive Antigen Identification
por: Mo, Zequan, et al.
Publicado: (2022)

The rise and fall of machine learning methods in biomedical research
por: Koohy, Hashem
Publicado: (2018)

Isotype Specific Assembly of B Cell Antigen Receptors and Synergism With Chemokine Receptor CXCR4
por: Maity, Palash C., et al.
Publicado: (2018)

Presence of MDSC associates with impaired antigen-specific T cell reactivity following COVID-19 vaccination in cirrhotic patients
por: Törnell, Andreas, et al.
Publicado: (2023)

A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize
por: Yang, Junbao, et al.
Publicado: (2018)

Cross-reactive neutralizing human monoclonal antibodies mapping to variable antigenic sites on the norovirus major capsid protein
por: Ford-Siltz, Lauren A., et al.
Publicado: (2022)

Tolerogenic Immunotherapy: Targeting DC Surface Receptors to Induce Antigen-Specific Tolerance
por: Castenmiller, Charlotte, et al.
Publicado: (2021)

Chromatin Accessibility Data Sets Show Bias Due to Sequence Specificity of the DNase I Enzyme
por: Koohy, Hashem, et al.
Publicado: (2013)

Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8(+) T Cell Tolerance Development
por: Damo, Martina, et al.
Publicado: (2021)

CrossDome: an interactive R package to predict cross-reactivity risk using immunopeptidomics databases
por: Fonseca, Andre F., et al.
Publicado: (2023)

NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability
por: Sommermeyer, Daniel, et al.
Publicado: (2013)

The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors
por: Oakes, Theres, et al.
Publicado: (2017)

Tumor Infiltrating Effector Memory Antigen-Specific CD8(+) T Cells Predict Response to Immune Checkpoint Therapy
por: Principe, Nicola, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1e7e65vvnl7gos3633rlmbeh0b