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Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity

Advanced prostate cancer initially responds to hormonal treatment, but ultimately becomes resistant and requires more potent therapies. One mechanism of resistance observed in around 10–20% of these patients is lineage plasticity, which manifests in a partial or complete small cell or neuroendocrine...

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Detalles Bibliográficos
Autores principales: Cyrta, Joanna, Augspach, Anke, De Filippo, Maria Rosaria, Prandi, Davide, Thienger, Phillip, Benelli, Matteo, Cooley, Victoria, Bareja, Rohan, Wilkes, David, Chae, Sung-Suk, Cavaliere, Paola, Dephoure, Noah, Uldry, Anne-Christine, Lagache, Sophie Braga, Roma, Luca, Cohen, Sandra, Jaquet, Muriel, Brandt, Laura P., Alshalalfa, Mohammed, Puca, Loredana, Sboner, Andrea, Feng, Felix, Wang, Shangqian, Beltran, Himisha, Lotan, Tamara, Spahn, Martin, Kruithof-de Julio, Marianna, Chen, Yu, Ballman, Karla V., Demichelis, Francesca, Piscuoglio, Salvatore, Rubin, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642293/
https://www.ncbi.nlm.nih.gov/pubmed/33144576
http://dx.doi.org/10.1038/s41467-020-19328-1