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Proteomic landscape of TGF-β1-induced fibrogenesis in renal fibroblasts

Transforming growth factor-β1 (TGF-β1) plays a premier role in fibrosis. To understand the molecular events underpinning TGF-β1-induced fibrogenesis, we examined the proteomic profiling of a TGF-β1-induced in vitro model of fibrosis in NRK-49F normal rat kidney fibroblasts. Mass spectrometric analys...

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Detalles Bibliográficos
Autores principales: Zhou, Shujun, Yin, Xiaoke, Mayr, Manuel, Noor, Mazhar, Hylands, Peter J., Xu, Qihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642370/
https://www.ncbi.nlm.nih.gov/pubmed/33149203
http://dx.doi.org/10.1038/s41598-020-75989-4