Discovery of driver non-coding splice-site-creating mutations in cancer

Non-coding mutations can create splice sites, however the true extent of how such somatic non-coding mutations affect RNA splicing are largely unexplored. Here we use the MiSplice pipeline to analyze 783 cancer cases with WGS data and 9494 cases with WES data, discovering 562 non-coding mutations th...

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Bibliografiska uppgifter
Huvudupphovsmän: Cao, Song, Zhou, Daniel Cui, Oh, Clara, Jayasinghe, Reyka G., Zhao, Yanyan, Yoon, Christopher J., Wyczalkowski, Matthew A., Bailey, Matthew H., Tsou, Terrence, Gao, Qingsong, Malone, Andrew, Reynolds, Sheila, Shmulevich, Ilya, Wendl, Michael C., Chen, Feng, Ding, Li
Materialtyp: Online Artikel Text
Språk:English
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Article
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642382/
https://www.ncbi.nlm.nih.gov/pubmed/33149122
http://dx.doi.org/10.1038/s41467-020-19307-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642382/
https://www.ncbi.nlm.nih.gov/pubmed/33149122
http://dx.doi.org/10.1038/s41467-020-19307-6

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