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Extracellular vesicles report on the MET status of their cells of origin regardless of the method used for their isolation

MET pathway is an important actionable target across many solid tumour types and several MET inhibitors have been developed. Extracellular vesicles (EVs) are proposed to be mini-maps of their cells of origin. However, the potential of EVs to report on the MET status of their cells of origin is unkno...

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Detalles Bibliográficos
Autores principales: Useckaite, Zivile, Mukhopadhya, Anindya, Moran, Barry, O’Driscoll, Lorraine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642384/
https://www.ncbi.nlm.nih.gov/pubmed/33149187
http://dx.doi.org/10.1038/s41598-020-75817-9