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Hydroxyurea treatment is associated with reduced degree of oxidative perturbation in children and adolescents with sickle cell anemia

Sickle cell anemia (SCA) is the most common inherited hemolytic anemia worldwide. Here, we performed an exploratory study to investigate the systemic oxidative stress in children and adolescents with SCA. Additionally, we evaluated the potential impact of hydroxyurea therapy on the status of oxidati...

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Detalles Bibliográficos
Autores principales: Vinhaes, Caian L., Teixeira, Rozana S., Monteiro-Júnior, Jay A. S., Tibúrcio, Rafael, Cubillos-Angulo, Juan M., Arriaga, María B., Sabarin, Adrielle G., de Souza, Amâncio J., Silva, Jacqueline J., Lyra, Isa M., Ladeia, Ana Marice, Andrade, Bruno B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642412/
https://www.ncbi.nlm.nih.gov/pubmed/33149225
http://dx.doi.org/10.1038/s41598-020-76075-5