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R-spondins are BMP receptor antagonists in Xenopus early embryonic development

BMP signaling plays key roles in development, stem cells, adult tissue homeostasis, and disease. How BMP receptors are extracellularly modulated and in which physiological context, is therefore of prime importance. R-spondins (RSPOs) are a small family of secreted proteins that co-activate WNT signa...

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Detalles Bibliográficos
Autores principales: Lee, Hyeyoon, Seidl, Carina, Sun, Rui, Glinka, Andrey, Niehrs, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642414/
https://www.ncbi.nlm.nih.gov/pubmed/33149137
http://dx.doi.org/10.1038/s41467-020-19373-w