Engineering cofactor supply and NADH-dependent d-galacturonic acid reductases for redox-balanced production of l-galactonate in Saccharomyces cerevisiae

d-Galacturonic acid (GalA) is the major constituent of pectin-rich biomass, an abundant and underutilized agricultural byproduct. By one reductive step catalyzed by GalA reductases, GalA is converted to the polyhydroxy acid l-galactonate (GalOA), the first intermediate of the fungal GalA catabolic p...

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Detalles Bibliográficos
Autores principales: Harth, Simon, Wagner, Jacqueline, Sens, Tamina, Choe, Jun-yong, Benz, J. Philipp, Weuster-Botz, Dirk, Oreb, Mislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642425/
https://www.ncbi.nlm.nih.gov/pubmed/33149263
http://dx.doi.org/10.1038/s41598-020-75926-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642425/
https://www.ncbi.nlm.nih.gov/pubmed/33149263
http://dx.doi.org/10.1038/s41598-020-75926-5

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