EPEC Recruits a Cdc42-Specific GEF, Frabin, To Facilitate PAK Activation and Host Cell Colonization

Enteropathogenic Escherichia coli (EPEC) is an extracellular pathogen that tightly adheres to host cells by forming “actin pedestals” beneath the bacteria, a critical step in pathogenesis. EPEC injects effector proteins that manipulate host cell signaling cascades to trigger pedestal assembly. We ha...

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Detalles Bibliográficos
Autores principales: Singh, Vikash, Hume, Peter J., Davidson, Anthony, Koronakis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642674/
https://www.ncbi.nlm.nih.gov/pubmed/33144373
http://dx.doi.org/10.1128/mBio.01423-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642674/
https://www.ncbi.nlm.nih.gov/pubmed/33144373
http://dx.doi.org/10.1128/mBio.01423-20

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