The Nontypeable Haemophilus influenzae Major Adhesin Hia Is a Dual-Function Lectin That Binds to Human-Specific Respiratory Tract Sialic Acid Glycan Receptors

NTHi is a human-adapted pathogen that colonizes the human respiratory tract. Strains of NTHi express multiple adhesins; however, there is a unique, mutually exclusive relationship between the major adhesins Hia and HMW1 and HMW2 (HMW1/2). Approximately 25% of NTHi strains express Hia, a phase-variab...

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Detalles Bibliográficos
Autores principales: Atack, John M., Day, Christopher J., Poole, Jessica, Brockman, Kenneth L., Timms, Jamie R. L., Winter, Linda E., Haselhorst, Thomas, Bakaletz, Lauren O., Barenkamp, Stephen J., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642680/
https://www.ncbi.nlm.nih.gov/pubmed/33144377
http://dx.doi.org/10.1128/mBio.02714-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642680/
https://www.ncbi.nlm.nih.gov/pubmed/33144377
http://dx.doi.org/10.1128/mBio.02714-20

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