Molecular homology between canine spontaneous oral squamous cell carcinomas and human head-and-neck squamous cell carcinomas reveals disease drivers and therapeutic vulnerabilities

Spontaneously occurring canine oral squamous cell carcinomas (COSCC) are viewed as a useful model for human head and neck squamous cell carcinomas (HNSCC). To date however, the molecular basis of COSCC remains poorly understood. To identify changes pertinent to cancer cells in COSCC, we specifically...

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Detalles Bibliográficos
Autores principales: Guscetti, Franco, Nassiri, Sina, Beebe, Erin, Rito Brandao, Inês, Graf, Ramona, Markkanen, Enni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642746/
https://www.ncbi.nlm.nih.gov/pubmed/33142242
http://dx.doi.org/10.1016/j.neo.2020.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642746/
https://www.ncbi.nlm.nih.gov/pubmed/33142242
http://dx.doi.org/10.1016/j.neo.2020.10.003

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