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Crystal structures of salts of bedaquiline

Bedaquiline [systematic name: 1-(6-bromo-2-meth­oxy­quinolin-3-yl)-4-(di­methyl­amino)-2-(naphthalen-1-yl)-1-phenyl­butan-2-ol, C(32)H(31)BrN(2)O(2)] is one of two important new drugs for the treatment of drug-resistant tuberculosis (TB). It is marketed in the US as its fumarate salt {systematic nam...

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Detalles Bibliográficos
Autores principales: Okezue, Mercy, Smith, Daniel, Zeller, Matthias, Byrn, Stephen R., Smith, Pamela, Bogandowich-Knipp, Susan, Purcell, Dale K., Clase, Kari L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642769/
https://www.ncbi.nlm.nih.gov/pubmed/33148877
http://dx.doi.org/10.1107/S2053229620013455