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Monothiol and dithiol glutaredoxin-1 from Clostridium oremlandii: identification of domain-swapped structures by NMR, X-ray crystallography and HDX mass spectrometry

Protein dimerization or oligomerization resulting from swapping part of the protein between neighboring polypeptide chains is known to play a key role in the regulation of protein function and in the formation of protein aggregates. Glutaredoxin-1 from Clostridium oremlandii (cGrx1) was used as a mo...

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Detalles Bibliográficos
Autores principales: Lee, Kitaik, Yeo, Kwon Joo, Choi, Sae Hae, Lee, Eun Hye, Kim, Bo Keun, Kim, Sulhee, Cheong, Hae-Kap, Lee, Won-Kyu, Kim, Hwa-Young, Hwang, Eunha, Woo, Ju Rang, Lee, Sung-Joon, Hwang, Kwang Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642778/
https://www.ncbi.nlm.nih.gov/pubmed/33209316
http://dx.doi.org/10.1107/S2052252520011598