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Enhancing the signal-to-noise ratio and generating contrast for cryo-EM images with convolutional neural networks

In cryogenic electron microscopy (cryo-EM) of radiation-sensitive biological samples, both the signal-to-noise ratio (SNR) and the contrast of images are critically important in the image-processing pipeline. Classic methods improve low-frequency image contrast experimentally, by imaging with high d...

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Detalles Bibliográficos
Autores principales: Palovcak, Eugene, Asarnow, Daniel, Campbell, Melody G., Yu, Zanlin, Cheng, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642784/
https://www.ncbi.nlm.nih.gov/pubmed/33209325
http://dx.doi.org/10.1107/S2052252520013184