Prioritizing long range interactions in noncoding regions using GWAS and deletions perturbed TADs

Genome-wide association studies (GWAS) have contributed significantly to predisposing the disease etiology by associating single nucleotide polymorphisms (SNPs) with complex diseases. However, most GWAS-SNPs are in the noncoding regions that may affect distal genes via long range enhancer-promoter i...

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Detalles Bibliográficos
Autores principales: Liu, Xuanshi, Xu, Wenjian, Leng, Fei, Hao, Chanjuan, Kolora, Sree Rohit Raj, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642798/
https://www.ncbi.nlm.nih.gov/pubmed/33209206
http://dx.doi.org/10.1016/j.csbj.2020.10.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642798/
https://www.ncbi.nlm.nih.gov/pubmed/33209206
http://dx.doi.org/10.1016/j.csbj.2020.10.014

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