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Disruption of STAT6 Signal Promotes Cardiac Fibrosis Through the Mobilization and Transformation of CD11b(+) Immature Myeloid Cells

Cardiac fibrosis is an important pathological basis of various cardiovascular diseases. The roles of STAT6 signal in allergy, immune regulation, tumorigenesis, and renal fibrosis have been documented. However, the function and mechanism of STAT6 signal in sympathetic overactivation-induced cardiac f...

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Detalles Bibliográficos
Autores principales: Zhang, Weiwei, Zhu, Baoling, Ding, Suling, Wang, Xiangfei, Wu, Jian, Zhu, Xiaowei, Zou, Yunzeng, Ge, Junbo, Tong, Minghong, Yang, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642801/
https://www.ncbi.nlm.nih.gov/pubmed/33192584
http://dx.doi.org/10.3389/fphys.2020.579712