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Physiological Ca(2+) Transients Versus Pathological Steady-State Ca(2+) Elevation, Who Flips the ROS Coin in Skeletal Muscle Mitochondria

Mitochondria are both the primary provider of ATP and the pivotal regulator of cell death, which are essential for physiological muscle activities. Ca(2+) plays a multifaceted role in mitochondrial function. During muscle contraction, Ca(2+) influx into mitochondria activates multiple enzymes relate...

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Detalles Bibliográficos
Autores principales: Li, Ang, Yi, Jianxun, Li, Xuejun, Zhou, Jingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642813/
https://www.ncbi.nlm.nih.gov/pubmed/33192612
http://dx.doi.org/10.3389/fphys.2020.595800