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Physiological Ca(2+) Transients Versus Pathological Steady-State Ca(2+) Elevation, Who Flips the ROS Coin in Skeletal Muscle Mitochondria
Mitochondria are both the primary provider of ATP and the pivotal regulator of cell death, which are essential for physiological muscle activities. Ca(2+) plays a multifaceted role in mitochondrial function. During muscle contraction, Ca(2+) influx into mitochondria activates multiple enzymes relate...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642813/ https://www.ncbi.nlm.nih.gov/pubmed/33192612 http://dx.doi.org/10.3389/fphys.2020.595800 |