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Mitochondrial Fission Factor (MFF) Inhibits Mitochondrial Metabolism and Reduces Breast Cancer Stem Cell (CSC) Activity

Elevated mitochondrial biogenesis and metabolism represent key features of breast cancer stem cells (CSCs), whose propagation is conducive to disease onset and progression. Therefore, interfering with mitochondria biology and function may be regarded as a useful approach to eradicate CSCs. Here, we...

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Detalles Bibliográficos
Autores principales: Sánchez-Alvarez, Rosa, De Francesco, Ernestina Marianna, Fiorillo, Marco, Sotgia, Federica, Lisanti, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642822/
https://www.ncbi.nlm.nih.gov/pubmed/33194575
http://dx.doi.org/10.3389/fonc.2020.01776