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Combining Auxin-Induced Degradation and RNAi Screening Identifies Novel Genes Involved in Lipid Bilayer Stress Sensing in Caenorhabditis elegans

Alteration of the lipid composition of biological membranes interferes with their function and can cause tissue damage by triggering apoptosis. Upon lipid bilayer stress, the endoplasmic reticulum mounts a stress response similar to the unfolded protein response. However, only a few genes are known...

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Detalles Bibliográficos
Autores principales: Venz, Richard, Korosteleva, Anastasiia, Jongsma, Elisabeth, Ewald, Collin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642917/
https://www.ncbi.nlm.nih.gov/pubmed/32958476
http://dx.doi.org/10.1534/g3.120.401635