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E3 Ubiquitin Ligases in Neurological Diseases: Focus on Gigaxonin and Autophagy
Ubiquitination is a dynamic post-translational modification that regulates the fate of proteins and therefore modulates a myriad of cellular functions. At the last step of this sophisticated enzymatic cascade, E3 ubiquitin ligases selectively direct ubiquitin attachment to specific substrates. Altog...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642974/ https://www.ncbi.nlm.nih.gov/pubmed/33192535 http://dx.doi.org/10.3389/fphys.2020.01022 |