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Isolation and Characterization of Multi-Protein Complexes Enriched in the K-Cl Co-transporter 2 From Brain Plasma Membranes

Kcc2 plays a critical role in determining the efficacy of synaptic inhibition, however, the cellular mechanisms neurons use to regulate its membrane trafficking, stability and activity are ill-defined. To address these issues, we used affinity purification to isolate stable multi-protein complexes o...

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Detalles Bibliográficos
Autores principales: Smalley, Joshua L., Kontou, Georgina, Choi, Catherine, Ren, Qiu, Albrecht, David, Abiraman, Krithika, Santos, Miguel A. Rodriguez, Bope, Christopher E., Deeb, Tarek Z., Davies, Paul A., Brandon, Nicholas J., Moss, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643010/
https://www.ncbi.nlm.nih.gov/pubmed/33192291
http://dx.doi.org/10.3389/fnmol.2020.563091