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Isolation and Characterization of Multi-Protein Complexes Enriched in the K-Cl Co-transporter 2 From Brain Plasma Membranes
Kcc2 plays a critical role in determining the efficacy of synaptic inhibition, however, the cellular mechanisms neurons use to regulate its membrane trafficking, stability and activity are ill-defined. To address these issues, we used affinity purification to isolate stable multi-protein complexes o...
Autores principales: | Smalley, Joshua L., Kontou, Georgina, Choi, Catherine, Ren, Qiu, Albrecht, David, Abiraman, Krithika, Santos, Miguel A. Rodriguez, Bope, Christopher E., Deeb, Tarek Z., Davies, Paul A., Brandon, Nicholas J., Moss, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643010/ https://www.ncbi.nlm.nih.gov/pubmed/33192291 http://dx.doi.org/10.3389/fnmol.2020.563091 |
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