Human perinatal stem cell derived extracellular matrix enables rapid maturation of hiPSC-CM structural and functional phenotypes

The immature phenotype of human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) is a major limitation to the use of these valuable cells for pre-clinical toxicity testing and for disease modeling. Here we tested the hypothesis that human perinatal stem cell derived extracellular mat...

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Detalles Bibliográficos
Autores principales: Block, Travis, Creech, Jeffery, da Rocha, Andre Monteiro, Marinkovic, Milos, Ponce-Balbuena, Daniela, Jiménez-Vázquez, Eric N., Griffey, Sy, Herron, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643060/
https://www.ncbi.nlm.nih.gov/pubmed/33149250
http://dx.doi.org/10.1038/s41598-020-76052-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643060/
https://www.ncbi.nlm.nih.gov/pubmed/33149250
http://dx.doi.org/10.1038/s41598-020-76052-y

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